Copy of HMD final exam questions blank

Copy of HMD final exam questions blank - HMD Final exam...

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HMD Final exam questions WEEK 2 PQ 1 Bioenergetics and thermodynamics If the D G' ° of the reaction A→ B is –40 kJ/mol, under standard conditions the reaction: A Is at equilibrium B Will never reach equilibrium C Will not occur spontaneously D Will proceed at a rapid rate E Will proceed spontaneously from left to right PQ 2 Phosphoryl group transfers and ATP The hydrolysis of ATP has a large negative ∆D G' °; nevertheless it is stable in solution due to: A Entropy stabilization B Ionization of the phosphates C Resonance stabilization D The hydrolysis reaction being endergonic E The hydrolysis reaction having a large activation energy PQ 3 Bioenergetics and thermodynamics Explain the relationships among the change in the degree of order, the change in entropy, and the change in free energy that occur during a chemical reaction. Ans: Entropy is a measure of disorder. Thus, if there is an increase in order there is a decrease in entropy. The greater the entropy of a system, the smaller its free energy. Thus, an increase in entropy during a reaction will result in a decrease in free energy.
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PQ 4 Glycolysis Glycolysis is the name given to a metabolic pathway occurring in many different cell types. It consists of 11 enzymatic steps that convert glucose to lactic acid. Glycolysis is an example of: A Aerobic metabolism B Anabolic metabolism C A net reductive process D Fermentation E Oxidative phosphorylation PQ 5 Glycolysis The anaerobic conversion of 1 mol of glucose to 2 mol of lactate by fermentation is accompanied by a net gain of: A 1 mol of ATP B 1 mol of NADH C 2 mol of ATP D 2 mol of NADH E None of the above PQ 6 Glycolysis There are a variety of fairly common human genetic diseases in which enzymes required for the breakdown of fructose, lactose, or sucrose are defective. However, there are very few cases of people having a genetic disease in which one of the enzymes of glycolysis is severely affected. Why do you suppose such mutations are seen so rarely? Ans: The glycolytic pathway is so central to all of cellular metabolism that mutations in glycolytic enzymes are lethal; embryos with such mutations would not survive. PQ 7 What is the rate limiting step? What happens at this stage?
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PQ 8 In an anaerobic muscle preparation, lactate formed from glucose labeled in C-3 and C-4 would be labeled in: A All three carbon atoms B Only the carbon atom carrying the OH C Only the carboxyl carbon atom D Only the methyl carbon atom E The methyl and carboxyl carbon atoms PQ 9 Which of the following statements is not true concerning glycolysis in anaerobic muscle? A Fructose 1,6-bisphosphatase is one of the enzymes of the pathway B It is an endergonic process C It results in net synthesis of ATP D It results in synthesis of NADH E Its rate is slowed by a high [ATP]/[ADP] ratio PQ 10 When a muscle is stimulated to contract aerobically, less lactic acid is formed than when it contracts anaerobically because: A Glycolysis does not occur to significant extent under aerobic conditions
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Copy of HMD final exam questions blank - HMD Final exam...

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