Genitourinary Cancers continued – Testicular cancer - Most common solid tumor in men between 15 – 35 years of age One of the most common curable forms of cancer due to its sensitivity to chemotherapy. 95 % are germ cell tumors can be seminomas or non seminomas. Most common primary testicular tumor is a seminoma. Malignant lymphoma is the most common bilateral testicular tumor overall. Non seminomas include renal cell carcinoma, teratoma, choriocarcinoma and mixed cell types. Risk factors: - History of prior testicular cancer. - Cryptorchidism (seminoma most common) - Association of extra gonadal germ cell tumors with Klinefelter and possibly Marfan’s syndrome. - Association of extragonadal germ cell tumors with hematological malignancy Clinical features: Unilateral painless testicular swelling or mass. Can be asymptomatic. Can present with acute testicular pain resulting from intratesticular hemorrhage Association with hydrocele in 20% of cases. Gynecomastia due to excessive beta hCG production. Note: Regional lymph nodes for testis is retroperitoneal lymph nodes. Metastasis is common to retroperitoneal lymph nodes. (Not inguinal lymph nodes).
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- Fall '19
- testicular cancer