ProteinSynthesisII

ProteinSynthesisII - PROTEIN SYNTHESIS ! Translation of...

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PROTEIN SYNTHESIS ! Translation of nucleic acid information
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RNA components of protein synthesis ! Messenger RNA (mRNA): gene-specific information ! Transfer RNA (tRNA): codon decoders ! Ribosomal RNA (rRNA): peptide bond synthesis
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Transfer RNA (tRNA) ! Transcribed from special tRNA genes (about 40; one for each codon, one or more for each amino acid). ! Matches codons with amino acids (called “adaptor” or “translator” molecule). ! Secondary and tertiary structure, generally cloverleaf; has “anticodon” at one end (3 bases complementary to codon), corresponding amino acid hooked onto the other end.
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Three bases make a “codon.” (Degenerate, but not ambiguous)
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Charging the transfer RNAs ! Activating enzyme; aa-tRNA synthetase ! Joins amino acids to tRNAs with the correct anticodons ! Provides some of the energy to form the peptide bond
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Ribosome structure Each ribosome consists of a large and small subunit Each subunit consists of 1 or 2 RNA molecules and 35-45 proteins
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Ribosome structure Each ribosome consists of a large and small subunit
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Initiation Translation begins with the formation of an initiation complex
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This note was uploaded on 06/18/2010 for the course BIS 103 taught by Professor Abel during the Spring '08 term at UC Davis.

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ProteinSynthesisII - PROTEIN SYNTHESIS ! Translation of...

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