Lecture 3 Resting Membrane Potential blanked out

Lecture 3 Resting Membrane Potential blanked out - The...

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Sheet1 Page 1 The Resting Membrane Potential Chapter 3 C Electrical signals electrical signals conductors because it is a good conductor of electrons, but h Neurons generate their electrical signals with _______ crossing the cell membrane c in water you get _______ ions, Na+, and ______ Neurons are bathed in a salty extracellular fluid containing Na+, Cl-, K+ (potassium), and Ca2+ (calcium) among others ( Ions can not cross the membrane other than through ____ _________ _ h Neurons have a membrane made up of a phospholipid bilayer h The phospholipid bilayer isolates the inside of the neuron from the extracellular fluid f Ions pass through ion channels to get through the membrane h Ion channels are _______ in the membrane h They are typically made up h Nerve cells (neurons) transmit information with h Nerve cells are not intrinsically good electrical h A copper telephone wire transmit information fast Whaths an ion? h Ion = atom or molecule with an electrical charge h Regular table salt is NaCl. When salt dissolves ions, Clh
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Sheet1 Page 2 of 4-6 subunits, forming a pore in the center h The type of subunits put together decides which ion can pass through h There are K+ selective channels, Na+ selective channels, Cl-selective channels etc. c Will the ion go through the ion channel? How ions move are decided by two forces: 1. ____________ 2. ____________ 2 distribute ions ______ in a solution of high concentration to regions of low concentration c Because ions are charged, ________ ___________ can move them There is a membrane dividing the solution in two compartments When channels are inserted in the membrane, ions move according to their electrical charge c h Diffusion acts to h Ions move from regions
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Sheet1 Page 3 The resting membrane potential If a microelectrode is inserted into a neuron at rest, the voltmeter shows a negative potential This potential is caused by uneven distribution of electrical charge across the membrane In this case it is -65 mV, that is, the inside is 65 mV more __________ than the outside _ Inside Outside There is 20 times more K+ and anions (A-, any negative ion) inside the cell compared to outside. But in this case there is no movement of ions
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This note was uploaded on 04/03/2008 for the course NEUROBIOLO Fund Neuro taught by Professor Schjott during the Spring '08 term at Rutgers.

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Lecture 3 Resting Membrane Potential blanked out - The...

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