PowerPoint slides 052610 and 052810

PowerPoint slides 052610 and 052810 - direction. •...

Info iconThis preview shows pages 1–14. Sign up to view the full content.

View Full Document Right Arrow Icon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Stereochemical Definitions and Terminology Stereoisomers: two molecules with the same connectivity, different arrangements of atoms in space Configuration: actual 3-dimensional arrangement of atoms and/or groups at a tetrahedral carbon Enantiomers: two molecules related as an object and its nonsuperimposible mirror image Chiral (adj.): not superimposible on mirror image, possesses “chirality” = handedness Achiral: superimposible on (identical to) its mirror image, i.e. without chirality
Background image of page 4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Optical Activity A bulk property of a chiral substance. A substance is “optically active” if it rotates plane- polarized light. Optical rotation is measured by a polarimeter A substance that rotates plane-polarized light in the clockwise direction is “dextrorotatory”. This is the (+)- direction. A substance that rotates plane-polarized light in the counterclockwise direction is “levorotatory”. This is the (-)-
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 12
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 14
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: direction. • Optical activity requires a molar xs of one enantiomer. Specific Rotation • Definition • i.e ., specific rotation = the rotation of a sample under standard conditions (1 g/mL, 10 cm cell). Converts extensive property to an intensive property. • A physical property of an enantiomerically pure substance. • Enantiomers have equal and opposite [  ] D ’s  obs  D l x c conc. (g/ml) path length (dm) = Stereochemical Possibilities (for a pure compound) • Stereochemical composition at the macroscopic level: – Enantiomerically pure: all molecules have the same configuration. – Enantiomeric excess: molar excess of one enantiomer over the other. – Racemic mixture: equimolar mixture of two enantiomers, [a] D = 0.00 o . An achiral substance....
View Full Document

This note was uploaded on 06/18/2010 for the course CHEM 225 taught by Professor Markdec during the Spring '10 term at University of Michigan-Dearborn.

Page1 / 14

PowerPoint slides 052610 and 052810 - direction. •...

This preview shows document pages 1 - 14. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online