lab_2_discussion - Laboratory Exercise 2 Skeletal Muscle...

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Laboratory Exercise # 2 Skeletal Muscle Mechanics 1. What is a skeletal muscle fiber? Present (and explain) a diagram that demonstrates the interaction between actin and myosin during contraction. What is the role of calcium, troponin, and tropomyosin? -individual muscle cells; refer to slide 11; Ca 2+ binds to Troponin C causing a conformational change that moves the troponin complex away from the myosin binding site on actin. 2. Present the basic anatomy of a motor neuron input into skeletal muscle (slide 7) How is each muscle fiber innervated? Depolarizations at plasma membrane travel to the middle of the muscle fiber through the T-tubule system. This propgogates depolarizations to the sarcoplasmic reticulum. SR serves as a source of calcium to initiate contraction, binding to tropomyosin. SR have ryanodine receptors that pick up depolarization signals, allowing efflux of calcion into cytoplasm from SR. What is a motor unit? Consists of the motor neuron and all muscle fibers it innervates. What are the advantages/disadvantages of large and small motor units? Large amounts of tension for large motor units, small allow for very fine muscle control. . eye movements. What kinds
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This note was uploaded on 06/23/2010 for the course NPB 101L taught by Professor Goldberg during the Spring '08 term at UC Davis.

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lab_2_discussion - Laboratory Exercise 2 Skeletal Muscle...

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