BIS 104 Lecture 3

BIS 104 Lecture 3 - B IS 104 Lecture 3 Homework: A cell...

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BIS 104 Lecture 3 Homework: A cell doubles in size (diameter 20um to 40um) (sphere) Vol = 4/3 (p)(r)^3 A) What is the effect on the surface area to volume ratio? B) What is the biological significance of this ratio? Notes: What are cells composed of? 1. Endoplasmic Reticulum a. RER (ribosomes + membrane) b. SER i. synthesis of lipids and sterols ii. enzymes for oxidation of biological molecules/detoxification 1. Ex: thalidomide (tested on pregnant rats – was OK) a. In humans, different effect. Liver metabolism is different in humans and rats. Teratogen caused birth defects. b. Prevents abnormal blood vessel growth. HIV treatment. iii. Calcium ion sequestration (uncontrolled release excess of this triggers cell death) 1. Ex: muscle (sarcoplasmic reticulum – modified SER in muscle cells) 2. Golgi Complex a. Stacks of double membranes with functionally distinct compartments (cisternae) b. Few – 100’s/ cell c. A processing and sorting plant for proteins and lipid distribution within the cell
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BIS 104 Lecture 3 - B IS 104 Lecture 3 Homework: A cell...

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