Slide Set I

Slide Set I - II. Patterns of Inheritance IV. Ecology I....

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Unformatted text preview: II. Patterns of Inheritance IV. Ecology I. Developmental Biology III. Evolution BSC 2011-02 Instructor: Dr. Trisha Spears TAs: Justin Fox Samantha Marrone I. Scientific Inquiry A. The scientific method & falsifiability B. Junk science; pseudoscience II. The Central Dogma (quick & brief review ) A. Defined B. DNA structure C. DNA replication D. Chromosomes 1. eukaryotic E. RNA 1. structure F. Transcription 1. terminology 2. the process G. Translation 1. the genetic code 2. the process H. Mutation I. Proteins Slide Set 1 Outline III. Cell Signaling & Communication A. Function B. Three stages 1. reception 2. transduction 3. response C. Examples IV. Gene Regulation in Eukaryotes A. Introduction B. Levels of control of gene expression 1. Chromosomal level (gene amplification) 2. Chromatin modification a. DNA methylation b. histone acetylation 3. Transcriptional control a. transcription factors b. enhancer sequences 4. Post-transcriptional control 5. Control of translation 6. Post-translational control Slide Set 1 Outline (contd.) THINK & SHARE WITH A NEIGHBOR(S):-come up with one Q that could be investigated by science (how?);- come up with one Q that could NOT be investigated by science (why not?) An acceptable alternative to deductive , hypothesis-driven (experimental) science: inductive reasoning (generalize from a large body of consistent observations) e.g., Cell Theory B. The Sc ie nt if ic M ethod: the scientific met hod is a step-w ise proc ess for experime ntat ion t hat is used to answer questions and e xplore observa ti ons. Hypoth esis: any propo sed expla natio n for an observe d phenome non. What scienti sts do is to prop ose and t hen e val uate hypot heses by exp erim ent atio n or furth er ob serv atio n. Theory : a hypot hesis or set o f h ypot heses t hat is consistent wit h vi rtu ally all of the available evi dence. Some time s ref erred to as a ? l aw o f nature?. ___ observe something ___ make a prediction __ experiment/test ___ formulate a hypothesis ___ ask a question __ revise hypothesis Why doesnt this %^$#!& flashlight work??!?!?!? Fig. 1.24 (1.25, 7th) 2. Falsifiability: this means that there must be some experiment or possible discovery that could prove the hypothesis/theory untrue. tests results not consistent; modify hypothesis W E IGNO RE SCI ENCE AT OUR OW N PERIL OTHER EXAMPLES MIXING SCIENCE & BUSINESS/POLITICS? THINK & SHARE with a neighbor(s) & come up with 2 other examples of junk science (the mix of science/business/politics). C. Pseu do science :- is indifferent to crit eria of valid evidence;- does not emp hasize me aningf ul, c ontrolled, repeata ble scientific experime nts....
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Slide Set I - II. Patterns of Inheritance IV. Ecology I....

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