FinalS10Akey

FinalS10Akey - BIS 101-001 (Engebrecht) Spring 2010 Form A...

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1 BIS 101-001 (Engebrecht) Final Spring 2010 Form A DO NOT OPEN UNTIL INSTRUCTED Fill out your name, student identification number and form letter on the blue Scantron Form with a #2 pencil. READ THE QUESTIONS CAREFULLY BEFORE YOU ANSWER. Fill in your answers on the scantron form with a #2 pencil. For each question only choose one answer (the best answer) and fill in your selection clearly and completely. If you change an answer, make sure you erase the original selection completely. There are 11 pages including this cover sheet and 43 questions to this exam worth 160 points. No calculators or cell phones during the exam. The exam will end promptly at 8pm. GOOD LUCK
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2 1. (3pts) Any heritable change in the DNA sequence: A. Mutation B. Frameshift C. Transition D. Transversion E. Epigenetics 2. (4pts) Chromosomal deletions: A. are most likely recessive B. will change linkage between genes C. are revertible D. A & B E. B & C 3. (4pts) Chromosomal duplications: A. are most likely recessive B. will change linkage between genes C. are revertible D. A & B E. B & C 4. (3pts) Experimental procedure in which only a specific type of mutant can survive A. Mutagenesis B. Screen C. Selection D. Forward Genetics E. Reverse Genetics 5. (4pts) A mutation that reverses the effect of another mutation and rarely generates mutant progeny when crossed to wild type A. Extragenic suppressor B. Intragenic suppressor C. Revertant D. tRNA suppressor 6. (4pts) Which are characteristic of a gene conversion event? A. 3:1 segregation B. 2:2 segregation C. Heteroduplex D. A & C E. B & C
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3 7. (4pts) Which are characteristic of a reciprocal exchange event? A. 3:1 segregation B. 2:2 segregation C. Heteroduplex D. A & C E. B & C 8. (3pts) Which below is an incorrect statement: A. DNA is a template for RNA B. RNA is a template for DNA C. RNA is a template for protein D. protein is a template for RNA E. DNA is a template for DNA Questions 9-12. You obtain the following sequence from the middle of YFG (Your Favorite Gene) that you isolated from a bacterium: 5’-G T C A A A A A T G G C T A G C T A G A-3’ 3’-C A G T T T T T A C C G A T C G A T C T-5’ 9. (3pts) How many possible ways are there to translate this sequence? A. 1 B. 2 C. 3 D. 6 E. 12 10. (6pts) Indicate the amino acid sequence encoded here – see codon table on last page. A. gln lys trp leu ala arg B. leu ser leu pro phe leu C. val lys asn gly stop leu D. ser lys met ala ser stop E. leu ala ser his phe cys 11. (4pts) Indicate the corresponding mRNA for this gene: A. 5’-GTCAAAAATGGCTAGCTAGA B. 5’-GUCAAAAAUGGCUAGCUAGA C. 5’-TCTAGCTAGCCATTTTTGAC D. 5’-UCUAGCUAGCCAUUUUUGAC E. 5’-CAGUUUUUACCGAUCGAUCU
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4 12. (3pts) You isolate the following mutation (bolded) in this sequence: 5’-G T C A A A A A A T G G C T A G C T A G A-3’ 3’-C A G T T T T T T A C C G A T C G A T C T-5’ This is a: A. missense B. transition
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FinalS10Akey - BIS 101-001 (Engebrecht) Spring 2010 Form A...

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