Outline01Lecture1-2 - individuals and our society Reading...

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BIS101-001/Engebrecht Spring 2010 Outline01Lectures1-2; Introduction and Mendel I. Class Organization Discussion of syllabus and all organizational matters concerning the course. Online Review Quiz due April 9 by 11:55pm. Reading for introduction. Chapter 1 in both 8 th and 9 th edition. II. Genetics Vocabulary Handout01BasicGeneticTerms provides basic terminology that will be used throughout this course. In addition, your textbook has an excellent glossary (8 th : 727-748; 9 th : 779-801). III. What is a gene? We will discuss the concept of a gene and the central dogma (DNA RNA protein). We will also discuss the impact of genomics on how we think of genes. Forward genetics : mutant identify gene analyze and infer function Reverse genetics : gene/protein make mutant (infer function from mutant phenotype) IV. Why should you care? We will discuss the impact that genetics and genomics have on you as
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Unformatted text preview: individuals and our society. Reading for Mendelian Genetics. Chapter 2, 27-40 in 8 th edition; Chapter 2, 37-44 and Chapter 3, 89-192. V. Mendelian Genetics – see Handout02Mendel a. Monohybrid segregation: 3:1 ratio in F2 Testcross = a cross between an individual of unknown genotype and a recessive homozygote, resulting in progeny in which each phenotypic class represents a different genotype. Reciprocal crosses = a cross in which the sexes of the parents are the reverse of another cross. b. Probabilities i. Punnett Square = a sort of cross-multiplication matrix used in the prediction of the outcome of a genetic cross, in which male and female gametes and their frequencies are arrayed along the edges. 1. Product rule 2. Sum rule ii. Branch diagram c. Dihybrid segregation: 9:3:3:1 in F2...
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