BIO 130 Lecture sheet

BIO 130 Lecture sheet - BIO 130 Lecture sheet April 1 2010...

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BIO 130 Lecture sheet April 1, 2010 Meiosis: operates normally to introduce genetic variability among human gametes Law of chromosome segregation: homologues segregate from each other during MI; this is a consequence of the convention that sister kinetochores orient to the same pole during MI, and thus, both sister chromatids of one homologue migrate to one pole and the two sister chromatids of its partner homologue migrate to the other spindle pole. Independent assortment of chromosomes: the process by which tetrads connect to the spindle is random, and thus the orientation of the two homologues of a given tetrad is made independent of the orientation of the homologues of another tetrad, and so on, and so on, for all of the tetrads of the MI cell. So, in the case of human spermatocytes or oocytes engaged in MI, there are many ways that the 23 tetrads can be oriented in the spindle. One of the figures is used to illustrate this point.
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