04-ProteinStructureS10b

04-ProteinStructureS10b - Proteins Levels of Protein...

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Proteins
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Levels of Protein Structure Primary structure (1°) Secondary structure (2°) Tertiary structure (3°) Quaternary structure (4°)
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Primary Structure Primary structure (1°) Amino acids linked via peptide bonds No R group involvement Information in a gene encodes primary structure Higher levels of structure are dependent on primary structure Sequence of amino acids determines secondary & tertiary structure
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Primary structure Figure 3.22
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Secondary protein structure Secondary structure (2°) Two forms of secondary structure Alpha-helix: coiled structure Produces relatively rigid rods Beta-sheets: parallel arrays of backbone Produces planar sheets Both stabilized by H-bonding
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Secondary structural elements Figure 3.22
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Tertiary Structure Structure that is the “shape” of a protein Arrangement of α -helices and β -sheets in space Final 3-D shape of single peptide For proteins of only 1 polypeptide: The highest level of structure
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Tertiary structure Figure 3.22
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04-ProteinStructureS10b - Proteins Levels of Protein...

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