111%20Exam%20#3%20S10%20Red%20Key-1

111%20Exam%20#3%20S10%20Red%20Key-1 - Exam 3 Biology 111...

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Exam 3 Biology 111 – Spring 2010 Dr. David H. Bos INSTRUCTIONS: Fill in your BIOL 111 code number and NOT your PUID in the section of the scantron sheet marked: Student Identification Number. The use of calculators, cell phones or other electronic devices is not allowed during the exam. Read each question carefully and choose the best answer. There are 34 questions on this exam. There is only one correct answer for each question. Do not fill in multiple answers, as they will be marked incorrect. Turn in only the answer sheet when you are done. You may keep the exam. Take your time, think and good luck! 1. Lymphocytes (white blood cells) do not “flow” freely through the blood vessels, but instead roll along the surface of the blood vessels in continuous contact with the epithelial cells that make up the lumen of the vessel. It is these epithelial cells that communicate to the lymphocytes where infection or damage has occurred. How would you characterize this communication? a. Synaptic b. Direct contact c. Paracrine d. Autocrine e. Endocrine 2. Which of the following is not a function of any membrane signaling receptors? a. Activate G-proteins b. Initiate a kinase cascade c. Transport the signaling molecule into the cell d. Transport ions into the cell e. Bind to receptors on adjacent cells 3. What would be the likely outcome if a cytoplasmic receptor was functionally normal except for a mutation that damaged the part of the receptor that binds to an inhibitor? a. It would increase the rate at which the signaling molecule would pass through the membrane b. It would decrease the rate at which the signaling molecule would pass through the membrane c. It would repress instead of stimulate gene expression when the signaling molecule was present d. It would be unable to bind to the signaling molecule, thereby failing to stimulate gene expression even when the signaling molecule was present e. The receptor would always be active and over-stimulate gene expression even when the signaling molecule was not present 4. Most receptor enzymes are what type of enzyme? a. Kinase b. G-protein coupled receptor c. Phosphorylase d. ATP synthase 1
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e. Transcription factor 5. What is the second step in receptor kinase signaling (i.e. after ligand binding)? a. Removal of a phosphate on a response protein b. Addition of a phosphate on a response protein c. G-protein activation d. Activation of another kinase in a kinase cascade e. Dimerization 6. If G-proteins were nonfunctional, the direct link between which to parts of the G-protein coupled receptor (GPCR) signaling system would be disabled? a.
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111%20Exam%20#3%20S10%20Red%20Key-1 - Exam 3 Biology 111...

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