LEC 06 Membrane Structure and Function

LEC 06 Membrane Structure and Function - MEMBRANE STRUCTURE...

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Unformatted text preview: MEMBRANE STRUCTURE AND FUNCTION Membrane structure Lipid bilayer: hydrophobic fatty acid interior Phosphate + hydrophilic group exterior Membrane structure Proteins incorporated into the bilayer ! Hydrophobic amino acid side chains ! Hydrophilic amino acid side chains ! Transmembrane alpha-helix ! Extracellular carbohydrates Fluid mosaic model Often, islands of protein complexes Membrane Functions 1. Platform for biochemical reactions Enzymes and other organelles (e.g. ribosomes, microtubules) attach to surface Membrane Functions 2. Sensing Receptors bind to "ligand" and transmit a signal across the membrane Membrane Functions 3. Cell recognition Receptors on different cells bind them together Membrane Functions 3. Cell recognition Receptors on different cells bind them together Membrane Functions 4. Differential permeability Channels and carriers transport substances across membranes ! Allows cells to adjust pH and salt concentrations ! Allows cells to keep functional chemicals inside ! Allows cells to take up food molecules and exclude toxins ! Allows cells to separate chemical reactions that otherwise would interfere with one another Osmosis...
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This note was uploaded on 07/08/2010 for the course BIS B16 taught by Professor Gerhart during the Winter '10 term at The University of British Columbia.

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LEC 06 Membrane Structure and Function - MEMBRANE STRUCTURE...

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