LEC 08 Concepts of Metabolism

LEC 08 Concepts of Metabolism - CONCEPTS OF METABOLISM A....

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CONCEPTS OF METABOLISM A. Metabolic pathways B. Control of metabolism C. Role of free energy
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A. Metabolic pathways Chemical reactions in a cell (e.g., 2000-4000 in a simple bacterium) ! Synthesis of fatty acids, amino acids, sugars; lipids, proteins, polysaccharides ! Breakdown of lipids, proteins, polysaccharides: food to be used for resynthesis; toxic wastes ! Other reactions: harvesting energy; repair; synthesis of “secondary compounds” for signalling
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A metabolic map
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A simplified metabolic map, as shown in your textbook (Fig. 6.15)
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Each dot in the diagram represents a compound. Each line represents a simple chemical reaction. The reactions are arranged in series, called pathways. A ---> B ---> C ---> D ---> F
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Each arrow represents one chemical reaction catalyzed by one enzyme.
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Sometimes pathways are more complex:
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Sometimes pathways are more complex:
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Basic principle: control metabolism by controlling the amount or activity of appropriate enzymes. 1. Control amount of enzyme protein
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LEC 08 Concepts of Metabolism - CONCEPTS OF METABOLISM A....

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