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LEC 09 RespirationI

LEC 09 RespirationI - Respiration RESPIRATION Breathing A...

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Respiration
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RESPIRATION ! Breathing ! A mechanism for providing ATP, NADH ! The release of free energy by oxidation- reduction reactions Example glucose + O 2 ---> CO 2 + H 2 O ! G=-673 Kcal/mole glucose Through coupled reactions, some of this free energy can be applied to the formation of ATP, NADH.
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Respiration Fermentation (aerobic) (anaerobic) Animals Plants Protists Fungi Some bacteria Fungi Some bacteria Animals and plants (for short periods only)
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Inputs glucose C 6 H 12 O 6 6 O 2 36 ADP + 36 P i Outputs 6 H 2 O 6 CO 2 36 ATP + 36 H 2 O Heat Overall reaction of respiration
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Glycolysis: the initial metabolism of glucose ! 10 reactions, each with its own soluble enzyme; all enzymes in endoplasm ! Converts 1 glucose (C 6 H 12 O 6 ) to 2 pyruvic acids (C 3 H 4 O 3 ) ! Partial oxidation of glucose (- 4e - ); reduction of NAD + to NADH + H + ! Forms 2 ATP (net: uses 2, produces 4) ! Produces waste heat 1 2 2 (ADP + P i ) 2 (ATP + H 2 O) 2 NAD + 2 NADH + H + Heat
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Glycolysis: the initial metabolism of glucose Uses ATP Makes ATP
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Pyruvic acid oxidation and Citric Acid Cycle !
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