LEC 10 RespirationII

LEC 10 RespirationII - RESPIRATION: SYNTHESIS OF ATP...

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RESPIRATION: SYNTHESIS OF ATP
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Respiration is a series of coupled reactions Carbon (in glucose) is oxidized ATP is formed from ADP plus phosphate O 2 CO 2 + H 2 O ADP + Pi ATP
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What happens to the respiration in animal or plant cells in the absence of oxygen? (a) Everything stops! (b) Glycolysis stops (c) Pyruvic acid oxidation and the citric acid cycle stop (d) The electron transport chain runs backward (e) Everything except the electron transport chain works as well as in the presence of oxygen
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Synthesis of ATP Anaerobic conditions (fermentation) ! Glycolysis depends on a supply of substrates: glucose, ADP, P i , NAD + ! NAD + , FAD present in only small amounts in cell. ! Therefore, NAD + must be regenerated from NADH to allow continued glycolysis, citric acid cycle operation. ! In air, electron transport chain regenerates NAD + and FAD by passing electrons to O 2. ! Without air, electron transport chain cannot oxidize NADH, FADH 2 ; citric acid cycle stops. ! Without air, some cells regenerate NAD + (from glycolysis only) by passing e - (+ H + ) to pyruvic acid ! Result: continued glycolysis, forming 2 ATP per glucose
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Muscle cells Reduction of pyruvate produces lactic acid
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LEC 10 RespirationII - RESPIRATION: SYNTHESIS OF ATP...

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