LEC 23 Regulating Protein Synthesis -- Eukaryotes

LEC 23 Regulating Protein Synthesis -- Eukaryotes - CELL...

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CELL CYCLES: MITOSIS, CYTOKINESIS AND MEIOSIS
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MITOSIS: The division of chromosomes in the nucleus S phase: duplication of DNA (to form two complete copies of each chromosome)
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DNA (chromatin) is wound into a manageable length ("condensed") by multiple stages of coiling ! Two daughter DNAs: two chromatids ! Joined at centromere (kinetichore)
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The "division of chromosomes" is really a separation of chromatids
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Prophase ! Chromatin condenses ! Centrosomes divide ! Asters (microtubules) form (in animal cells)
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Prometaphase ! Spindle forms ! Nuclear envelope disappears ! Nucleolus disappears Metaphase ! Spindle fibers attach to kinetochores ! Chromosomes move to equitorial plane
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Anaphase ! Centromeres divide ! Chromosomes move to poles ! Cytokinesis begins Telophase ! Chromosomes uncoil ! Nuclear membrane, nucleolus reform ! Spindle disappears
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Same process in pictures from the 8th edition:
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chromatids ! Cohesin; Securin; Separase
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LEC 23 Regulating Protein Synthesis -- Eukaryotes - CELL...

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