Chapter 17 - RNAmolecules that are not translated into...

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Chapter 17 Initiation: After RNA polymerase binds to the promoter, the DNA strands unwind, and the polymerase initiates RNA synthesis at the start point on the template strand Elongation: The polymerase moves downstream, unwinding the DNA and elongating the RNA transcript 5’ to 3’ direction. In the wake of transcription, the DNA strands re-form a double helix. Termination: Eventually the RNA transcript is released and the polymerase detaches from the DNA Bacteria have a single type of RNA polymerase that synthesizes not only mRNA but also other types of RNA that function in protein synthesis, such as ribosomal RNA. Eukaryotes have three types of RNA polymerase in their nuclei. RNA pol II is used for mRNA synthesis, the others polymerases transcribe
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Unformatted text preview: RNAmolecules that are not translated into protein. RNA Polymeras Binding and Initiation of Transcription The promoter of a gene includes within it the transcription starting point the nucleotide where RNA synthesis actually begins and typically extends several dozen nucleotide pairs upstream from the start point. The promoter serves as a binding site for RNA polymerase and determines where transcription starts, but it also determines which of the two strands of the DNA helix is used as the template. In bacteria, the RNA polymerase itself specifically recognizes and binds to the promoter, in eukaryotes, a collection of transcription factors mediate the binding of RNA polymerase and the initation of transcription....
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This note was uploaded on 07/10/2010 for the course BIO 204 taught by Professor O'neal during the Spring '07 term at SUNY Stony Brook.

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