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Unformatted text preview: A variety of factors that can cause neural tube defects But wait! Theres more! TIMP-3 is a matrix metalloproteinase inhibitor. TIMPs and MMPs form a balance in the cell that regulates ECM tissue remodeling. Only present in dorsal structures during Xenopus embryogenesis. In situ hybridization of TIMP-3 in developing Xenopus embryos...
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- Fall '09