Lec 14 - Breakdown of amino acids carbon skeletons are...

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Nitrogen metabolism breakdown of proteins and amino acids
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Protein breakdown half-life of some rat liver enzymes
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Protein breakdown and transport in the body
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Breakdown of proteins into amino acids by ubiquitin tags dragging proteins into the 20S proteasome Chemistry Nobel Prize 2004. Irwin Rose, Avram Hershko, Aaron Ciechanover
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Breakdown of proteins into amino acids inside the 26S proteasome
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Breakdown of amino acids: Alanine is converted to pyruvate in the liver to supply substrate for gluconeogenesis
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Breakdown of amino acids: Glucogenic amino acids, grouped by site of entry
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Breakdown of amino acids: Glucogenic amino acids, grouped by site of entry
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Unformatted text preview: Breakdown of amino acids: carbon skeletons are utilized ammonia is released by oxidative deamination Breakdown of his, arg, pro, glu, gln, orn Breakdown of thr, gly, ala, ser, cys Breakdown of amino acids: ammonia is either directly released (marine organisms) or released as urea (mammals) or uric acids (birds) The urea cycle channels ammonia into urea Net reaction NH 3 + HCO 3-+ aspartate + 3 ATP Æ urea + AMP + 2 ADP + 2 Pi + PP i + fumarate Urea cycle: Activation of bicarbonate costs 2 ATP The urea and TCA cycle are linked in different organelles...
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Lec 14 - Breakdown of amino acids carbon skeletons are...

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