8th lecture_Fiehn BIS103 photosynthesis_winter 2008

8th lecture_Fiehn BIS103 photosynthesis_winter 2008 -...

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Synthesis of Carbohydrates and Gluconeogenesis
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Both glycolysis and gluconeogenesis are thermodynamically feasible at the same time but use different routes, Lecture 3 3 out of 10 reactions in glycolysis are exergonic + 2 ATP -6ATP but do not happen at the same time but use different routes, because control points regulate relative fluxes according to needs
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Third bypass of reverse ‘glycolysis reactions’ in gluconeogenesis: Glucose-6-phosphatase
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Increase in acetyl-CoA concentration activates gluconeogenesis at 1 st bypass and inactivates glycolysis at PDH complex
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Control of gluconeogenesis by glucagon/cAMP cascade at the 2 nd bypass using Fructose-2,6-bisphosphate
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Synthesis of Carbohydrates and Gluconeogenesis
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Plants can generate glucose from fatty acids via the glyoxylate shunt …animals can’t
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2 Further reading: Heldt Plant Biochemistry Lehninger CO 2
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8th lecture_Fiehn BIS103 photosynthesis_winter 2008 -...

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