14 DNA - BIO 1140 TOPIC 14 SLIDE 1 TOPIC 14: CHEMISTRY OF...

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BIO 1140 TOPIC 14 SLIDE 1 TOPIC 14: CHEMISTRY OF DNA ¾ DNA structure and chemistry ¾ nucleotides ¾ polynucleotides ¾ the DNA molecule ¾ Chargoff principle ¾ complimentary base pairs BIO 1140 TOPIC 14 SLIDE 2 To understand the workings of a complex macromolecule, be it a protein, a polysaccharide, a lipid, or a nucleic acid, it is essential to know the exact construction of the molecule. ‘What a wonderful sentence with which to start an essay’! BIO 1140 TOPIC 14 SLIDE 3 GENES & CHROMOSOMES ¾ A chromosome contains a single DNA molecule, parts of which represent the individual genes (although there are overlapping genes). ¾ chromosome — a single, genetically specific DNA molecule to which are attached, in eukaryotes, a large number of basic (positively charged) structural proteins ( histones ) as well as other proteins. (can be seen when used in context of mitosis or meiosis) ¾ gene — that entire nucleic acid sequence of a DNA molecule that that is necessary for the synthesis of a functional gene product be it a protein or an RNA.
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This note was uploaded on 07/21/2010 for the course SCIENCE BIO1140 taught by Professor Fenwick during the Winter '09 term at University of Ottawa.

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14 DNA - BIO 1140 TOPIC 14 SLIDE 1 TOPIC 14: CHEMISTRY OF...

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