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week 4 - 4 - Week 4 Acidity of Carboxylic Acids Draw some...

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Week 4 July 15, 2010 Acidity of Carboxylic Acids Draw some examples of carboxylic acids. Why are they acidic? What is a typical p K a ? For each of the following carboxylic acids, change the structure slightly so that the acid becomes more acidic . Explain why that change is effective. OH O OH O F OH O For each of the following carboxylic acids, change the structure slightly so that the acid becomes less acidic . Explain why that change is effective. OH O F OH O Reading : Sections 20.1 and 20.4 38
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Week 4 July 15, 2010 Carboxylic Acid Derivatives Draw some examples of each of the following carboxylic acid derivatives: ester (and lactone) amide (and lactam) acid chloride acid anhydride nitrile Reading : Section 21.1 39
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Week 4 July 15, 2010 Some Syntheses of Carboxylic Acids and Nitriles You already know some ways of making carboxylic acids. What are they? Here’s another way of making a carboxylic acid. Can you draw the mechanism? What is special about this method for making carboxylic acids?
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