Chapter_16_17%20Lymphatic%20System_Body%20Defenses

Chapter_16_17%20Lymphatic%20System_Body%20Defenses - Organs...

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1 Organs of the Immune System The Lymphatic System • A specialized network of tissues & vessels scattered throughout the body One way system to the heart Starts at blind lymph capillaries in intercellular spaces ends when the lymph joins the blood circulation to the heart • Serves almost all body regions except Lymphatic Capillaries Single layer of endothelial cells Large gaps allow larger molecules to get through Endothelial cells overlap & act as one-way valves opened by interstitial fluid pressure, allowing fluid to enter but not to leave The Lymphatic System What is lymph? What are lacteals? What is chyle? Which substance emulsifies the dietary fats? and from where is it released? What are some of the differences between blood capillaries and lymphatic capillaries? Functions of the Lymphatic System Protection from infection: – lymph nodes act as filters removing pathogens and tumor cells from lymph Fluid balance : lymphatic capillaries drain lymph back into the blood circulation Transporting dietary lipids : digested lipids absorbed into lacteals blood Lymphatic Vessels • Beaded appearance due to due to the one way valves • May be deep or superficial • Named according to their location, e.g. mammary lymphatic vessels femoral lymphatic vessels in the thigh tibial lymphatic vessels in the leg
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2 Lymphatic (Collecting) Ducts Right lymphatic duct: – receives lymph from the upper right quadrant right subclavian vein Thoracic duct: – receives lymph from the rest of the body left subclavian vein Cisterna chyli? Function? Lymphatic Flow Structure of a Lymph Node Regional Lymph Node Groups • Clusters of lymph nodes that service a particular area; e.g. – Cervical nodes – Axillary nodes – Inguinal nodes – Mesenteric nodes – Tracheobronchial nodes What are a buboes? The Spleen • A spongy, purple soft organ in the LUQ Largest lymphoid organ Filters blood instead of lymphatic fluid – thus has only efferent lymphatic vessels Periarteriolar Lymphoid Sheath ( PALS ): a sheath of lymphoid cells surrounding each of the arterioles region of phagocytic activity which sets the stage for an immune response for blood-borne Ags The Spleen Red pulp : RBCs filtration site White pulp : contains B lymphocytes & macrophages
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3 The Spleen What are the 4 main functions of the spleen? Splenomegaly? Splenectomy? Its effects? The Thymus Low in the throat Site of T-lymphocytes maturation triggered by what? Plays a key role in the development of the immune system before birth & during the first few months Attains its full size at 2 years of age , and then shrinks to a nearly undetectable size by puberty The Reticuloendothelial System – Tissue Macrophage System/ Mononuclear Phagocyte System/ Monocyte-Macrophage System
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Chapter_16_17%20Lymphatic%20System_Body%20Defenses - Organs...

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