1 Introduction

1 Introduction - 1 Introduction to Bioinformatics/ Elements...

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1 Introduction to Bioinformatics/ Elements of Bioinformatics Introduction Brian Wong [email protected]
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2 References Baxevanis, A.D., and Ouellette, B.F.F. (2005) Bioinformatics - A Practical Guide to the Analysis of Genes and Proteins , 3rd ed., John Wiley and Sons, NY. Mount, D.W. (2004) Bioinformatics: Sequence and Genome Analysis , 2nd ed., Cold Spring Harbor Lab. Press, N.Y.
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3 On-line educational resources 2can bioinformatics educational resources at European Bioinformatics Institute (EBI) Teaching resources and on-line tutorials at National Center for Biotechnology Information (NCBI) http://www.ncbi.nlm.nih.gov/Education/ http://www.ebi.ac.uk/2can/home.html
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4 What is bioinformatics? The application of computer technology to the management and analysis of biological data.
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5 What is bioinformatics? • Bioinformatics is an inter-disciplinary subject. •I n t e g r a t e s : –B io logy – Mathematics, probability and statistics – Algorithms
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6 Syllabus • Biological databases and query tools • Pairwise sequence alignment – Dotplot, optimal alignment • Database search – BLAST, FASTA • Substitution matrices • Multiple sequence alignment – Progressive alignment • Phylogenetic prediction • Gene prediction • Prediction of regulatory sequences
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7 Course requirement • 2 – 3 assignments – 30% of final marks • 2-hour written examination – 70% of final marks
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8 Why bioinformatics? Sequence analysis methods appeared
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This note was uploaded on 07/29/2010 for the course BIOC BIOC1805 taught by Professor Dr.brianwong during the Summer '09 term at HKU.

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1 Introduction - 1 Introduction to Bioinformatics/ Elements...

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