6 Dot Plot - 1 Introduction to Bioinformatics Elements of...

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1 Introduction to Bioinformatics/ Elements of Bioinformatics Pairwise sequence alignment – Dot Plot
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2 References Mount D.W. (2004) Bioinformatics: Sequence and Genome Analysis. 2 nd ed. Cold Spring Harbor Lab. Press, N.Y. Chapter 3. Baxevanis, A.D., and Ouellette, B.F.F. (2005) Bioinformatics - A practical guide to the analysis of genes and proteins (3rd ed). John Wiley and Sons, NY. Chapter 11. Altschul S.F., and Gish W. (1996) Local alignment statistics. Methods in Enzymology 266: 460-480.
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3 Sequence alignment Seq a GGCCTCCTC |||| || | Seq b GGCC-CCAC An alignment GGCCTCCAC GGCCTCCT C GGCC- CCAC A T One possible evolutionary history T Seq a Seq b
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