References•Mount D.W. (2004) Bioinformatics: Sequence and Genome Analysis. 2nd ed. Cold Spring Harbor Lab. Press, N.Y. Chapter 9.•Baxevanis, A.D., and Ouellette, B.F.F. (2005) Bioinformatics - A practical guide to the analysis of genes and proteins (3rd ed). John Wiley and Sons, NY. Chapter 5.•Mathe C., Sagot M-F, Schiex T., and Rouze P. (2002) Current methods of gene prediction, their strengths and weaknesses. Nucleic Acids Research 30: 4103-4117.
Gene prediction•given a DNA sequence– predict the protein coding regions: •which strand is used as template?•which reading frame is used? •which region is protein coding (exon)?– predict the regulatory regions
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