BIO 234 Lec 20 six slides.pdf - Renal Physiology THE URINARY SYSTEM 2 Three Organic Waste Products 1 2 3 Organic Waste Products Are dissolved in

BIO 234 Lec 20 six slides.pdf - Renal Physiology THE...

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1 THE URINARY SYSTEM 2 Dr. Gregory Karapetian Lecture 20 Renal Physiology Three Organic Waste Products: 1. Urea 2. Creatinine 3. Uric acid Organic Waste Products Are dissolved in bloodstream Are eliminated only while dissolved in urine Removal is accompanied by water loss Renal Physiology The Kidneys Usually produce concentrated urine 1000 1400 mOsm/L (four times plasma concentration) Osmolarity Is the osmotic concentration of a solution Total number of solute particles per liter Expressed in osmoles per liter (Osm/L) or milliosmoles per liter (mOsm/L) Renal Physiology Kidney Functions To concentrate filtrate produced by glomerular filtration Failure here would lead to fatal dehydration Absorb and retain valuable materials for use by other tissues Sugars and amino acids Delivers via our blood Renal Physiology Basic processes of urine formation : 1. Filtration 2. Reabsorption 3. Secretion Renal Physiology Filtration (Step 1) Hydrostatic pressure forces water through membrane pores Small solute molecules pass through pores Larger solutes and suspended materials are retained Occurs across capillary walls As water and dissolved materials are pushed into interstitial fluids
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