Moritz5Notes - Biology 1BEvolution Lecture 5 (March 5,...

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Moritz Lecture 5 Notes – page 1 Biology 1B—Evolution Lecture 5 (March 5, 2010), Genetic Drift and Migration Mutation What is mutation? Changes in the coding sequence Changes in gene regulation, or how the genes are expressed as amino acids, proteins, etc. Changes in the copy number of genes (only a segment of a chromosome being copied and put somewhere else within the genome) Changes in the number of genomes copied, such as polyploidy in plants, making them 4N or 8N Simplistic DNA Diagram: Agouti’s presence is based on one gene (two alleles), and both would need to be recessive to completely stop suppression of Mc1r, leading to a very dark colored mouse Some mutations could increase expression of Agouti, which would lead to a very light colored mouse (paler than normal) Mc1r can have dominant mutations that increase the sensitivity to the activation hormone, thus further increasing the production of melanin Migration In evolutionary terms, migration is defined as movement that will result in gene flow, or the movement of genes from one place to another Regulation Genes Introns (transcribed, but not translated) mRNA for protein translation Thousands of Base Pairs Exons
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Moritz Lecture 5 Notes – page 2 Roles in Evolution
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Moritz5Notes - Biology 1BEvolution Lecture 5 (March 5,...

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