Preparation of 4-Bromo-2-Chloroaniline

Preparation of 4-Bromo-2-Chloroaniline - Preparation of...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Preparation of 4-Bromo-2-Chloroaniline Purpose: The purpose of this lab was to convert the acetamido group of 4-bromo- 2-chloroacetanilide into an amino group. This reaction takes place with concentrated hydrochloric acid in ethanol. The main reason to turn the acetamido group into an amino group is so that further substitution is feasible in the number 6 site of the ring without deactivating the properties of the halogens being a factor during additional reactions. The central reaction for their lab was: Procedure: In this experiment we obtained 11.20g of pure 4-bromo-2- chloroacetanilide without using or yield from the previous experiment. We then placed the crystals in a round bottom flask with 20mL of 95% ethanol solution with 13mL of concentrated hydrochloric acid. We turned the heat on to about 150 degrees Celsius and added the stir bar in and established our reflux apparatus. We had to retrieve a larger condensing column because the one we had did not fit. This had no effect on our experiment though because whether larger or smaller the condensing column only serves to cool entering vapors back into an aqueous state. During the reflux we set up another heater with 200 mL of deionized water in it to have it ready for when we needed it in the next part of the experiment. The reflux lasted for about half an hour before we decided to terminate.
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern