AZTSynthesis - HO O O O N HN TrO MsO O S Cl O O CH 3 O N N...

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Thymidine AZT (TrCl) SYNTHESIS OF AZT FROM THYMIDINE NaOH, H 2 O DMSO S N 1 Reaction S N 2 Reaction S N 2 Reaction S N 2 Reaction S N 2 Reaction S N 1 Reaction Hydrolysis Reaction O N HO HO HN O O O O N HN O HO O O N MsO TrO HN O O O O N N TrO O O O N HN HO N 3 O Cl CH 3 S O O Cl O O N HN TrO
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Unformatted text preview: HO O O O N HN TrO MsO O S Cl O O CH 3 O N N 3 TrO HN O O (MsCl) Et 3 N Et 3 N (MsCl) LiN 3 DMF H 3 O + APPLICATION OF REACTIONS OF ALCOHOLS AND ETHERS...
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This note was uploaded on 08/11/2010 for the course CHEM 30B Chem 30B U taught by Professor Miguelgarciagaribay during the Spring '10 term at UCLA.

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