Unformatted text preview: comparison group was involved. Rationale: no information of baseline rate of recovery from sore throat without medicine. Failure to compare with other group 3. The best answer is c Rational: page 139 –In addition to blinding the subjects, we also want to mask (or blind) the observers or data collectors in regard to which group a patient is in. This is called “double blinding” 4. The best answer is b. Rational: Direction of the risk, the relationship of disease (endometrial cancer) and estrogen use are known. 5. The best answer is b. Rational page 140 First is that of carryover: For example, if a subject is changed from therapy A to therapy B and observed under each therapy, the observations under therapy B will be valid only if there is no residual carryover from therapy……Finally, the planned crossover design is clearly not possible if the new therapy is surgical or if the new therapy cures the disease....
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- Summer '09
- Clinical trial, best answer, estrogen, Sojung Suk