Concepts from Lecture 20

Concepts from Lecture 20 -...

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What are the conditions that must be met for a population to be in Hardy‐Weinberg equilibrium? 1. Random mating 2. No Mutation 3. No Gene flow 4. Extremely large population 5. No Natural Selection HW is a simple model – we use it as a Null model –which is to say it is our initial hypothesis that allele and genotype frequencies are not changing. If they are changing, then we look at these different factors as ways to explain why it is changing. Violations of the first conditions are considered Neutral evolutionary changes which is basically that there is NO Natural Selection but instead just neutral demographic processes. HW equilibrium is the state where the allele frequencies and genotype frequencies stay the same. This doesn’t mean the allele frequencies or genotype frequencies are all equal, just that they don’t change from generation to generation. Random mating – every individual has equal and independent chance of mating of an individual of opposite sex. So the probability that any male and any female would mate is just 1 / (Num Males) * 1 / ( Num Females). So if there are 12 males and 16 females, the chance of any particular male – female mating is 1 / 12 * 1 / 16. Random mating insures that
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This note was uploaded on 08/15/2010 for the course BIO 5c taught by Professor Zhu/cardullo/rao during the Spring '08 term at UC Riverside.

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Concepts from Lecture 20 -...

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