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Review Guide - Lecture 4 - Acid-base Homeostasis, Blood gas analysis - 2010

Review Guide - Lecture 4 - Acid-base Homeostasis, Blood gas analysis - 2010

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Review Guide and Self Assessment Quiz Acid-Base Homeostasis Blood gas analysis Acidosis and alkalosis High Yield – Acid - Base Clinical Biochemistry – Core Biochemistry – Metabolic acid-base disorders
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Concept, Knowledge and Objectives Production of acids in our body. The buffering system used in our body to maintain pH. Normal plasma pH, [H+], [HCO3-] and pCO2. Normal anion gap and normal osmolality. The role of lung respiration and kidney excretion in acid-base homeostasis Acids production in the body – Normal plasma pH, stomach fluid. The equilibrium calculation of pCO 2 -bicarbonate,[CO2] with Henderson- Hasselbalch eq. Definition and determination of metabolic and respiratory acidosis/alkalosis . How anion gap responses to acidosis and alkalosis. The physiological responses to acidosis and alkalosis Different causes that lead to acidosis and alkalosis Differential diagnosis of acidosis and alkalosis disorders.
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1. A teenage boy took overdose of salicylic acid (aspirin) and become acidosis. Salicylic acid has a pKa of 3. What will be his anion gap in blood?
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