This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: 1/27 Quiz 4 due Thursday @ 9am (may need to read ahead to ch. 6) Learning objectives for first exam posted on moodle Protein Structure • Hydrogen bonds in the peptide backbone stabilize the secondary structure Native and denatured proteins • Native – properly folded and functional • Denatured – unfolded and does not function (involves the breaking of weak bonds) • Fig 5.23 Roles of Weak Bonds in Biological Systems • Are easily made and broken at physiological temperatures • Provide specificity • If “weak” interactions were “strong,” would crystallize the contents of a cell • Attract and attach substrates to enzymes • Determine molecular shape – a compromise between backbone and side groups Clicker: Bonds responsible for primary structure peptide & covalent Bonds responsible for secondary structure Hydrogen H-bonding in 2degree structure Atoms in peptide backbone 1/27 F reezing The freezing problems confronting fish Fish in -3 super cold water, if you introduce and ice cube, ice forms and the fish dies Fish in -1.5 super cold water, if you introduce an ice cube and bring it into contact with the fish the fish died Fish in -3 super cold water, a fish has ingested ice crystals and it dies Fish come into contact with algae on ice, how do they keep from freezing?...
View Full Document
- Spring '07
- Proteins, Bovine spongiform encephalopathy, Prion, Transmissible spongiform encephalopathy, super cold water