0421 final

0421 final - 04/21 final exam Calcium homeostasis o...

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04/21 final exam Calcium homeostasis o Calcitonin Peptide hormone Produced in the thyroid gland Lowers blood calcium levels o Parathyroid hormone (PTH) Peptide hormone Produced in the parathyroid gland Raises blood calcium levels Bone o Bone matrix- collagen principle component o Calcium phosphate o Bone is continuously being remodeled Osteoporosis o Particular problem in elderly women o Age-related alteration in bone homeostasis o Can also result from glucocorticoid administration o Estrogens important in prevention of postmenopausal osteoporosis o Thought to act by opposing the calcium-mobilizing, bone-reabsorbing effect of PTH Hormones soluble in lipids o Steroids Intracellular receptors Cycling between the cytoplasmic and nuclear compartments Activated receptor in the nucleus activates specific genes by binding to DNA Ligands for steroid receptors Steroid hormones Thyroid hormones Vitamin D Retinoic acid steroid effects o produced by steroids increasing protein synthesis o slow in onset due to this testes o produce androgens, e.g., testosterone support sperm formation; male secondary sex characteristics
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This note was uploaded on 08/22/2010 for the course BIOL 1201 taught by Professor Wishtichusen during the Spring '07 term at LSU.

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0421 final - 04/21 final exam Calcium homeostasis o...

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