# LAB 8 - LAB 8 NOTE These labs are known for high failure...

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LAB 8 NOTE: These labs are known for high failure rates. Therefore, if I show an example using data, a graph, etc… yours may be totally different depending upon mine and yours success with the lab. So don’t freak if your data is completely different from mine. And therefore the analysis of results sometimes may need to be answered differently since you base your analysis off your data and not mine. DISCLAMIER: DO NOT CHEAT! Table 8.1 Example: Table 8.1 Phenotypes Allele Frequency Based on the H-W Equation Tasters Nontasters p q # % # % 0.47 0.53 Class Population 14 78 4 22 American Population 0.55 0.45 0.67 0.33 *p calculated by taking square root of the percent of nontasters. *q calculated by taking p and subtracting it from one. Topics for discussion 1. What is the percentage of heterozygous tasters (2pq) in your class? q^2 = .22 q = .47 p = .53 (.47)(.53) = .25 .25 X 2 = .5 50% are heterozygous tasters. 2. What percentage of the north American population is heterozygous for the taster trait? q^2 = .45 q = .67 p = .33 (.67)(.33) = .22 .22 X 2 = .44 44% are heterozygous tasters. Case 1 Generation # AA # Aa # aa 1 Aa 5 13 8 2 Aa 8 8 7 3 Aa 4 14 5 4 Aa 7 11 8 5 aa 4 13 6 Case 1 Allele frequency: # of A alleles present at the 5 th generation # of offspring with genotype AA (4) times (2) = 8 A alleles

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# of offspring with genotype Aa (13) times (1) = 13 A alleles Total = 21 A alleles P = # of A alleles / # of alleles (students times 2) P = 21 / (13+4+6)(2) P = .46 # of a alleles present at the 5 th generation # of offspring with genotype aa (6) times (2) = 12 a alleles # of offspring with genotype Aa (13) times (1) = 13 a alleles Total = 25 a alleles Q = # of a alleles / # of alleles (students times 2) Q = 25 / (13+4+6)(2) Q = .54 Questions 1. What does the hardy-weinburg equation predict for the new p and q? The equation predicts frequency of AA is 46% and aa is 54%. Note: The answers to these questions depend upon YOUR results. 2. Do your results obtained in this simulation agree? If not, why? Yes, the results agree.
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LAB 8 - LAB 8 NOTE These labs are known for high failure...

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