PS3_addendum

PS3_addendum - Additional Notes and Hints Problem 1 I am...

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Additional Notes and Hints Problem 1 I am asking you to propose a mechanism for the stringent response (section 9.10) and am specifically asking you how ppGpp might DIRECTLY participate in the regulatory events that occur downstream of ppGpp production. You will not find the answer simply by reading section 9.10 but you will need to carefully read the section to gather important details to include in your mechanism. Look at figure 9.20; it tells you that ppGpp mediates 2 distinct regulatory events: downregulation of rRNA synthesis and upregulation of amino acid biosynthetic operons. How can ppGpp be DIRECTLY involved? I would suggest reviewing sections 9.3 – 9.5, and also 9.9, to get some ideas! You should be able to describe your mechanism in 200 words or less (my answer was 150 words). Problem 2. Several people have asked for clarification of the first sentence of this problem (which is application question #1 at the end of chapter 11). The lactose and maltose operons both contain inducible gene products.
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This document was uploaded on 08/25/2010.

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PS3_addendum - Additional Notes and Hints Problem 1 I am...

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