ch369_sum10_ch9_notes

ch369_sum10_ch9_notes - Chapter 9 “Overview of...

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Unformatted text preview: Chapter 9. “Overview of metabolism” Chapter 10. “Glucose metabolism” (also known as glycolysis) The next few classes will be about metabolism. Next exam - Chapters 6 to 10 Metabolism • Metabolism is all the chemical reactions taking place in an organism • Heterotrophs – use organic carbon as food (example = humans) • Autotrophs – use inorganic carbon as food (examples = plants, some bacteria) • Two subtypes of metabolism within cell – Catabolism (complex ==> simple molecules) – Anabolism (simple ==> complex molecules) Why would we want to make ATP? What’s it good for? One goal of metabolism is to make ATP. Useful energy is released when the phosphoanhydride bonds are cleaved. Hydrolysis of ATP releases energy. energy + + One thing that ATP is useful for is driving the conformational changes in the “motor protein” myosin that we met in Chapter 5. (the Na + /K + transporter uses the energy released in ATP hydrolysis to move ions against a concentration gradient) Also, active transport requires energy, which may be provided by ATP hydrolysis. Active transport can work against a concentration gradient. There is something else that ATP can be used for: Energy released in ATP hydrolysis can be used to drive chemical reactions that would otherwise be thermodynamically unfavorable. Illustrate this important point with an example. (not spontaneous) Example: Cells need to produce glucose-6-phosphate from glucose....
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ch369_sum10_ch9_notes - Chapter 9 “Overview of...

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