Ch369-ch 14-lipids 1 - Lipid metabolism Chapter 14 F a t t y a c id s F A s a n d t r ia c y lg ly c e r o ls T A G s F A s a n d T A G s s t o r e

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Chapter 14. Lipid metabolism.
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FAs and TAGs store a lot of energy in a small volume. Denser energy storage than carbohydrates (fats can be packed together tightly without intervening water). Compare 38 kJ/g in fats versus 16 kJ/g in carbohydrates. Difference is mostly because fats are more reduced (less oxidized) than carbohydrates. Also, fats require less water for packing. Fatty acids (FAs) and triacylglycerols (TAGs) Fatty acid
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Sources of lipids for metabolism. Fatty acids (FAs) and triacylglycerols (TAGs) in the diet. Triacylglycerols are also synthesized in the liver. Triacylglycerols are stored in fat cells. Fatty acid
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Lipid metabolism in animals Transport is a problem - fats are not soluble in water (too hydrophobic). Systems are needed for their absorption and transport to where they can be metobolized. (fats are metabolized mostly in skeletal muscles, heart, liver) Bile is used to assist in breaking down insoluble fat globules.
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Most fats enter intestine as globules. Bile is used to assist in breaking down insoluble fat globules.
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Most fats enter intestine as globules. Bile is used to assist in breaking down insoluble fat globules. Bile Produced by the liver and stored in the gall bladder. Enters GI tract at start of small intestines. Composed of micelles of lecithin, cholesterol, protein, bile salts, inorganic ions and pigments. Purpose is to break fat globules into smaller ones. Smaller size means a larger surface area which is easier to attack.
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Bile acts like a detergent, breaking up fat globules.
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Liprotein lipase (or just “lipase”) - an enzyme produced in the pancrease. Cleaves triacylglycerols (TAGs) to produce fatty acids (FAs). monoacylglycerol is also produced by lipase.
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- Chylomicrons , VLDLs (very low density lipoprotein particles) LDL (low density lipoprotein particles). HDL
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This note was uploaded on 08/26/2010 for the course CH 369 taught by Professor Kbrowning during the Spring '07 term at University of Texas at Austin.

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Ch369-ch 14-lipids 1 - Lipid metabolism Chapter 14 F a t t y a c id s F A s a n d t r ia c y lg ly c e r o ls T A G s F A s a n d T A G s s t o r e

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