bio 35 - BIO 311C Spring 2010 Lecture 35 Monday 26 Apr 1...

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BIO 311C Spring 2010 Lecture 35 – Monday 26 Apr. 1
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Illustration of Information Flow in Prokaryotic and Eukaryotic Cells prokaryotic cell eukaryotic cell All information flow in prokaryotic cells occurs in the cytoplasmic matrix. Relatively little processing of information molecules occurs in prokaryotic cells. Information flow and processing in eukaryotic cells is partitioned between the nucleoplasm and the cytoplasmic matrix. Additional systems of information flow in eukaryotes occur within the matrix of mitochondria and in the stroma of plastids (not shown in these illustrations). These organellar systems of information flow are very similar to the information flow systems in prokaryotic cells. Textbook Fig. 17.3, p. 329 * 5
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Flow of Information in Cells amino end carboxylic acid end Strand of DNA containing coded information (read in the 3' 5' direction). The strand of DNA that is transcribed is called the template strand, or the plus strand, or the sense strand. Strand of mRNA containing coded information (written from DNA and read to polypeptide chain in the 5' 3' direction). The three- nucleotide units of RNA are called codons. Polypeptide chain (written from RNA starting from the amino- terminal end). * transcription translation From textbook Fig. 17.4, p. 329. 6
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codon 1 codon 2 codon 3 codon 4 Key to the genetic code portion of a molecule of messenger RNA Use of the genetic code makes it possible to determine the sequence of amino acids in a polypeptide chain by knowing the sequence of nucleotides in a molecule of mRNA. codon 1 codes for the amino acid "trp". Can you use the code to determine the amino acids generated by codons 2, 3 and 4? 5' 3' Use of the Genetic Code U U U U U G G G G C C C Textbook Fig. 17.5, p. 330 * 7
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DNA mRNA minus strand plus strand polypeptide chain By knowing the information content of a portion of any one information molecule, it is possible to deduce the information content of the corresponding portion of any of the other information molecules. In order to deduce the information content of all other information molecules
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This note was uploaded on 08/29/2010 for the course BIO 49720 taught by Professor Brand during the Spring '10 term at University of Texas.

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bio 35 - BIO 311C Spring 2010 Lecture 35 Monday 26 Apr 1...

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