BISC 330 Spring 2010 Lecture 1

BISC 330 Spring 2010 Lecture 1 - BISC 330: Biochemistry...

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BISC 330: Biochemistry Spring Semester 2010 USC Lecture: Monday, 11 January 2010 1.Introduction to BISC 330 2.Review course syllabus 3.Start Chapter 1 material…
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BISC 330 BIOCHEMISTRY - SPRING 2010 Lecture Syllabus Topics : Biochemical bonds and reactions. Interactions with water molecules. Structure/function of DNA, RNA, proteins, lipids and carbohydrates. Enzyme kinetics and mechanisms. Enzyme cofactors and vitamins. Enzyme regulatory strategies. Cell structure, membranes and organelles. Protein biosynthesis and targeting to membranes and organelles. Glucose and O 2 production by photosynthesis in plant chloroplasts. Glucose oxidation and ATP production: glycolysis, citric acid cycle & oxidative phosphorylation. Ribose biosynthesis from glucose by pentose phosphate pathway. Professors: Dr. John Petruska, Tel: (213) 740-5189, Email: petruska@usc.edu Office: MCB (RRI) 119B, Office Hours: RRI 121 Tues/Thurs 11am - 1pm Dr. Steven Goodman, Tel: (213) 740-3867, Email: sgoodman@usc.edu Office: DEN 4108, Office Hours: TBA Dr. Angel P. Tabancay, Jr., Tel: (213) 740-8352, Email: tabancay@usc.edu Office: ZHS 256, Office Hours: ZHS 256 Monday 3-5pm Text : Berg, Tymocko & Stryer, BIOCHEMISTRY (6th ed. 2007)
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Lecturer, Date Subject Chapter AT, Jan 11 Biochemical bonds and reactions 1.1-1.3 13 Water, pH and acid/base equilibria 1.3 15 DNA discovery & genomic revolution 1.4 18 No Lecture - Martin Luther King Day 20 Amino acid structures & properties 2.1 22 Primary structure of proteins 2.2 25 Secondary structure 2.3 27 Tertiary & quaternary structures 2.4-2.6 29 Protein purification methods 3.1 Feb 1 Amino acid analysis & sequencing 3.2 AT, Feb 2 MIDTERM EXAM #1 4:00-5:30pm TBA 175 points
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AT, Feb 3 Protein structure determination 3.3-3.6 5 DNA & RNA structure & purification 4.1,4.2 8 DNA replication & gene expression 4.3-4.6 JP, Feb 10 Intro. to thermodynamics & kinetics 8.1-8.3 12 Enzyme kinetics: M-M model 8.4 15 No Lecture - Presidents Day 17 Enzyme kinetics with inhibitors 8.5 19 Enzyme catalytic strategies 9.1-9.4 22 Enzyme regulatory strategies 10.1--10.4 24 Carbohydrate structures 11.1-11.4 26 Fatty acids, lipids & membranes 12.1-12.5 Mar 1 Coenzymes & vitamins 15.1-15.4 JP, Mar 2 MIDTERM EXAM #2 4:00-5:30pm TBA 175 points
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Mar 3 Cell structure & organelles: nucleus, mitochondria & chloroplasts 12.6 18.1,19.1 5 Cell membranes & vesicles, RER, Golgi, lysosomes, micro-tubules & -filaments. 11.3, 30.6 34.2, 34.3 8 Protein targeting to membranes 30.5, 30.6 10 Photosynthesis: Chlorophyll absorbs light used to split covalent O-H bonds in H2O 19.1,19.2 12 PS I,II & Cyt bf action: pump H+, store H- 19.3 15-19 NO LECTURES - SPRING BREAK 22 ATP synthesis using H+ current 19.4 24 Glucose synth. using ATP & H- in NADPH 20.1,20.2 26 Ribose synthesis by Pentose Phos. Pway 20.3 29 Ribose synthesis by Pentose Phos. Pway 20.3 JP, Mar 30 MIDTERM EXAM #3 4:00-5:30pm TBA
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This note was uploaded on 08/30/2010 for the course BIO 320 taught by Professor Wu during the Spring '10 term at USC.

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BISC 330 Spring 2010 Lecture 1 - BISC 330: Biochemistry...

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