DS8 and DS9 - DS8 Metabolism: Anabolism: synthesis...

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DS8 Metabolism : Anabolism: synthesis Catabolism: degradation 1 st law : energy can be transferred or transformed but can’t be destroyed 2 nd law : energy transfer or transformation leads to increase randomness Δ G= Δ H–T Δ S Δ G (free energy) = Δ H (enthalpy,potential energy, heat) –T Δ S (entropy,randomness) Spontaneous(ΔG?0), nonspontaneous (ΔG?0) Endogonic (ΔG?0), exergonic (ΔG?0) Endothermic (ΔH?0), exothermic (ΔH?0)
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Chemical reaction equilibrium: keq Enzyme : lower the free energy of activation Temperature, salt, pH, substrate, cofactors Km, Vmax Substrate specificity, interaction force (ionic,H-bond, van der Waals) Enzyme regulation: conformation change Activator Inhibitor: Competitive: km?, Vmax?, binding to ? Noncompetitive: km?, Vmax? binding to? Allosteric regulation, feedback reguation
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This note was uploaded on 08/31/2010 for the course BIO 49810 taught by Professor Satasivan during the Spring '10 term at University of Texas at Austin.

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DS8 and DS9 - DS8 Metabolism: Anabolism: synthesis...

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