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BB2920 Lect2notesF10new

BB2920 Lect2notesF10new - DNA Structure Replication DNA...

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Traits can be transferred : 1928 Griffith & Streptococcus pneumonia DNA: Structure & Replication DNA: Structure & Replication Ch.7 Ch.7 What is the chemical nature of this heritable change ? How can we determine what a gene is? 1944 Avery - experimental system? Heredity dependent on genes - Heredity dependent on genes - what is the composition of a gene? what is the composition of a gene?
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• 1944 Avery - experimental system? DNA: Structure & Replication DNA: Structure & Replication Ch.7 Ch.7 1. 2. 3. 4. 5. Take home = Gene comprised of DNA What is the composition of a gene? What is the composition of a gene?
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What is DNA? DNA - “deoxyribonucleic acid” 1. 2. 3. nitrogenous base a. b. 4. antiparallel double helix 5. Phosphodiester linkage 6. 7. A T, C G 8. Chargaff’s rules DNA: Structure & Replication DNA: Structure & Replication Ch.7 Ch.7 1. 2.
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How is DNA organized? • double helix • stacking of bases • major groove & minor groove Does DNA structure fulfill requirements ? 1. faithful replication complementary 2. informational content sequence 3. variation mutation/cross-over DNA: Structure & Replication DNA: Structure & Replication Ch.7 Ch.7
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How are genes organized?
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