{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Lect4notes - Gene Function Activity Gene How do mutations...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
How do mutations affect the informational content How do mutations affect the informational content of a gene/protein? of a gene/protein? Mutations a. base changes - silent - missense - nonsense b. frameshifts - additions - deletions c. chromosomal anomalies - insertion - deletion - inversion - translocation Gene Function: Activity Gene Function: Activity
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Mutations and Ploidy a. recessive (b) - phenotype only observed in homozygote b / b Genotype name Phenotype + / + homozygote wild-type b / + b / b How do mutations affect gene function? How do mutations affect gene function? b. Dominant (C) - phenotype observed in heterozygote C / C + or C / + Genotype name Phenotype + / + homozygote wild-type C / + C / C * haplo-insufficient * haplo-insufficient * hemizygous hemizygous gene name allele Gene Function: Activity Gene Function: Activity
Background image of page 2
Mutations and Protein activity . a. loss-of-function alleles: - - - How do mutations affect the informational content How do mutations affect the informational content of a gene?
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}