CHEMISTRY Departmental Seminar M.S. Final Seminar Ms. Min Zhang San José State University Adviser: Dr. Joseph Pesek Characterization of carboxylic acid phases on a hydride surface for HPLC A UDA column, which has undecynoic acid groups attached to a silica hydride surface, is chromatographically characterized in this research, and the retention mechanism is discussed. The polar molecules tested on the UDA column were metabolites (amino acids, carbohydrates), peptides, proteins, nucleosides, nucleotides, and galactosemia biomarkers. Different detection and retention modes were employed according to the spectroscopic and structural properties of the solutes. The
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This note was uploaded on 09/08/2010 for the course CHEM 285 at San Jose State University .