Lecture_18 - 3 Factors affecting solubility A Structural...

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1 3. Factors affecting solubility A. Structural effects As discussed earlier, molecular structure determines the polarity. The solubility is governed by interactions between the solute and the solvent. Like dissolves like is a general guiding rule for predicting solubility. A working example: Solubility of the various vitamins in water: Two major classes: fat soluble (vitamins A, D, E, K ) water soluble (vitamins B, C ) Hydrophilic Hydrophobic Vitamin A Vitamin C Vitamin A: overwhelmingly C and H hydrophobic , soluble in body fats and not in water. Vitamin C: many O H and C O bonds polar, and thus hydrophilic and water soluble. • The water soluble vitamins (B and C) can be easily excreted. • Vitamins A, D, E and K can be stored in fats (excess hypervitaminosis ).
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2 B. Pressure effects Very little effect of pressure on the solubilities of solids and liquids. • An increase in pressure significantly increases the
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This note was uploaded on 09/07/2010 for the course FAS chem 201 taught by Professor Sultan during the Summer '07 term at American University of Beirut.

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Lecture_18 - 3 Factors affecting solubility A Structural...

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