Hw #3 CHEM 157

Hw #3 CHEM 157 - Maria Alvarado A07011197 April 22, 2010...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Maria Alvarado A07011197 April 22, 2010 Chem 157 Homework #3 1. Though both fungal and mammalian FAS are type I, their structures vary. Fungal FAS is a while the mammalian FAS is . The mammalian FAS is 1 protein with 2 identical subunits whereas the fungal FAS is 2 proteins with 2 multifunctional subunits. They also vary in size, the mammalian FAS is smaller than the fungal FAS. These type I FAS differ from those present in bacteria and plants, type II FAS. Bacterial and plant FAS have 7 proteins whereas type I FAS have 1 protein. The size between type I and type II FAS vary as well; type II FAS are larger than type I. In type II fatty acid synthase, the ACP sequentially transfers the acyk-chain intermediates amongst the different enzymes whereas in type I fatty acid synthase the ACP is integrated within the catalytic domains of the enzymes. Also, in type I FAS, the PPT moieties reach into the active site cleft of KS whereas in type II FAS these moieties are rotated inward and the acyl chains...
View Full Document

Ask a homework question - tutors are online