exam 3 - The Watson-Crick Model of DNA structure • DNA is...

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Chapter 9- DNA: The molecule of Heredity How did scientists discover that genes are made of DNA? Avery, McLeod, and McCarty What is the transforming material? o Cell extracts treated with protein, carbohydrate, and RNA digesting enzymes could still transform bacteria o Cell extracts treated with DNA- digesting enzymes lost their transforming ability o Concluded that DNA transforms bacteria What is the structure of DNA Nucleotide Bases in DNA o Each nucleotide contains a phosphate, deoxyribose sugar, and N-containing base A nucleotide strand o Strands are always assembled from P end to S end o Covalent bond b/n the sugar of one nucleotide and the phosphate of a second
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Unformatted text preview: The Watson-Crick Model of DNA structure • DNA is a helix of 2 nucleotide strands • Complementary base pairs hold the 2 nucleotide strands together • Complementary strands run in opposite directions Base Pairing in DNA • Chargaffs rule o A-T o G-C • Adenine and thymine always form pairs o 2 H bonds • Cytosine and Guanine always form pairs o 3 H bonds X-ray Diffraction of DNA • Maurice Wilkins and Rosalind Franklin knew that DNA formed some sort of helic by the pattern seen in X-ray diffraction The Discovery of DNA •...
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This note was uploaded on 09/11/2010 for the course BIOL 1001 taught by Professor Minor during the Spring '08 term at LSU.

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exam 3 - The Watson-Crick Model of DNA structure • DNA is...

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